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KMID : 1024520180270110999
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Journal of the Environmental Sciences
2018 Volume.27 No. 11 p.999 ~ p.1005
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Effects of Antarctic Ocean Krill Meal with NaF Oral Administration on Serum and Tissues in Rats
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Kang Dong-Soo
Jin Dong-Hyeok
Oh Da-Young
Lee Young-Guen
Kim Han-Soo
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Abstract
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The purpose of this study was to probe the influences of krill (Euphausia superba) meal with NaF oral administration on a dose-effect relationship between fluoride levels of krill meal and serum enzyme activity such as alkaline phosphatase (ALP), aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) in rats fed experimental diets for 5 weeks. There were no significant decreases in the activities of ALP, AST, ALT, and LDH in sera among krill meal diet groups (KF10, KF20, KF30). However, these groups were significantly (p<0.05) lower enzyme activities than normal diet (ND) plus NaF 10 mg group (NF). The fluoride levels of serum and organ tissues (liver, brain, heart, lung, kidney) in NaF 10 mg groups (NF, KF10, KF20, KF30) were significantly increased by adding krill meal in comparison with normal diet group. The results indicate that a difficult to found toxicity to the tissues from krill meal diet groups.
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KEYWORD
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Krill (Euphausia superba) meal, Serum enzyme activity, Fluoride, Aminotransferase (AST, ALT)
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